The OECD GLP Principals define a physical/chemical test system as an “apparatus used for the generation of physical/chemical data”. It is the equipment or apparatus to which the test item or reference item is applied during the conduct of a study. Due to the number of different types of studies that are conducted, a complete list is not possible. However, some examples of physical/chemical test systems which may be used to evaluate the physical/chemical properties of a test item may include basic equipment such as pH meters, spectrophotometers and other analytical equipment and/or highly sophisticated and complex equipment such as gas chromatography–mass spectrometry, or those which utilise amplification and analysis of genetic material.
