There is a separate guidance on master cell banks. Which is not Q7A. Even when we did not have Q7A and when we didn’t have other ICH guidance documents dealing with the establishment of the master cell bank, I remember when I was in the field many years ago, whenever I did an inspection of a fermentation process, I always thought of the inspection in the laboratory and actually observed when they take stock culture and they incubate that in Erlenmeyer flasks and they start the fermentation process in the laboratory. And I would ask questions about the establishment of the master cell bank. So, again, I don’t think that’s going to change the way FDA does inspections, it might change somewhat our focus that we may not focus so much those initial steps versus the later, but again, I think at the point where we initiate the inspection that’s not going to change.
