Yes. The USP General Notices provide in summary form the basic guidelines for interpreting and
applying the standards, tests, assays, and other specifications of the USP so that these general statements do
not need to be repeated in the various monographs and chapters throughout the book. Where exceptions to the
General Notices exist, the wording in an individual monograph or general test chapter takes precedence.
This concept is further emphasized in the introduction to the General Information chapters which states, “The
official requirements for Pharmacopeial articles are set forth in the General Notices, the individual
monographs, and the General Tests and Assays chapters of this Pharmacopeia”. The General Tests and
Assays chapters are those numbered lower than 1000.