Yes. Some examples of specific IEMs that medical foods could be used to manage
involve amino acid/protein, organic acid, or fatty acid metabolism. These IEMs
primarily require significant restriction of particular amino acids and/or total protein
such as in phenylketonuria (phenylalanine restriction), ornithine transcarbamylase
deficiency (nonessential amino acid restriction), methylmalonic acidemia (isoleucine,
methionine, threonine, and valine restriction), or significant modification of fatty
acids/total fat such as in very long-chain acyl-CoA dehydrogenase deficiency (long
chain fatty acid restriction with an increase in medium chain fatty acid levels).
