Yes. Differing yield ranges [ICH Q7, Section 8.14] may be described and justified in the manufacturing procedure/master batch record explaining the ranges [ICH Q7, Section 6.41]. For example, the first batch in the series of production of batches of the same material (campaign) may leave residual material in the equipment, resulting in a low yield in the first batch and contributing to an increased yield in a subsequent batch of the campaign.
