No. Registration by a paper system is still available. FDA regulations require that owners,
operators, or agents in charge must submit their registration, registration renewal, update, and
cancellation to FDA electronically beginning on January 4, 2020, unless FDA has granted a
waiver under 21 CFR 1.245 (21 CFR 1.231(a)(2); 21 CFR 1.234(d); 21 CFR 1.235(d)). If FDA
has granted a waiver, registrations and registration renewals may be submitted through mail or
fax (see 21 CFR 1.231(a)(2); 21 CFR 1.234(d); 21 CFR 1.235(d)). However, FDA continues to
encourage use of the electronic format because it is more efficient and provides for immediate
submission of the registration information.
