No. Under 21 CFR 1.227, each foreign facility is required to have only one U.S. agent for food
facility registration purposes. However, having a single U.S. agent for FDA registration purposes
does not preclude a facility from having multiple brokers for other business purposes. A foreign
facility is not required to conduct all of its business in the U.S. through the U.S. agent designated
for purposes of registration (see 21 CFR 1.227 and Comment 86 in the preamble to the Interim
Final Rule; 68 FR 58894 at 58915).
