The objective of process validation is to generate evidence of consistency. You can only show
consistency by producing multiple batches in exactly the same way. So in this example, you
should try to run all three batches at the target value of 65 degrees. You normally would have
already tested the temperature ranges in the development phase. So if you’ve already done that
beforehand during the development, there’s no expectation to challenge the defined ranges
during the actual process validation.
