The validation process typically includes swabs. You may get to the point where you can correlate swab results that with rinse water for normal cleaning between batches, between lots. But, certainly, the validation should include swab samples. A lot will depend on what it is you’re trying to clean. In other words, what might the residues be and what is the equipment? Some are easier to develop by looking first at rinse water and then later just using swabs to confirm that you’re getting adequate cleaning. Also, don’t overlook the value of visual inspection or other alternative tests like challenge with riboflavin because these, in some environments, can be very useful aids in cycle development.
