Regarding registering a trial on ClinicalTrials.gov, in a multicenter trial, is the PI at the lead site responsible, or the sponsor?

In a multicenter trial in which the Sponsor initiates the trial and its employees conduct the trial, the Sponsor generally registers the trial. The Sponsor, however, may designate the PI to be the Responsible Party and to be responsible for registering the trial. NIH/FDA considers holders of an IND or IDE the Responsible Party.