According to the WHO guidance for Treatment of Diarrhoea: A Manual for Physicians and Other Senior Health Workers zinc supplementation “can be given as syrup or dispersible tablet, whichever is available or affordable”. However, as the International Pharmacopoeia (Ph. Int.) and United States Pharmacopeia (USP) monographs for zinc sulfate tablets require a disintegration time of 60 seconds or less (very fast disintegrating), applicants should submit applications for either zinc tablets that meet the above disintegration time specification or oral zinc solutions.
