An API manufacturer performing sampling of its starting material within a room not equipped with any type of air handling system. In addition, there’s no environmental monitoring. Is this acceptable?

Section 7.3 states that sampling should be conducted at defined locations and by procedures
designed to prevent contamination of materials sampled and contamination of other materials.
There are not necessarily any requirements for environmental monitoring, unless the material that
you were sampling was so sensitive that you needed that environmental monitoring to prevent the
contamination of that material.