Like 21 CFR 211, Q7A allows a manufacturer to accept COAs on materials provided they
establish the reliability of the supplier’s analysis by qualifying the supplier’s test results at
appropriate intervals. Section 7.3 of Q7A states, “Complete analysis should be conducted on at
least three batches before reducing in-house testing. However, at a minimum, a complete
analysis should be performed at appropriate intervals and compared with the certificates of
analysis.”