No and the problem is negative controls are usually in strong minority – there are not too many of them that are used. And when you don’t have many and depending on where you positioned within your testing scheme, the negative controls may not be enough. It is certainly a good thing to do, but the negative control really ought to be a manipulative control especially in cases where you are actually testing a sample of sterilized water in a similar kind of container to that of the sample container so that they are manipulated or handled in exactly the same fashion and not in abbreviated fashion or different fashion. Very often the negative control does not consist of all manipulations associated with regular testing so there is limited value to it. Having environmental monitoring or something like that during the testing is another very key element to being able to examine in the lab.
